【佳学基因检测】1型神经纤维瘤病成人的社会功能

品牌基因检测怎么样排队

分析肿瘤基因检测位点的全面性与准确性, 明白《Res Dev Disabil》在. 2013 Oct;34(10):3393-9.发表了一篇题目为《1型神经纤维瘤病成人的社会功能》肿瘤靶向药物治疗基因检测临床研究文章。该研究由Natalie A Pride, Hilda Crawford, Jonathan M Payne, Kathryn N North等完成。促进了1型神经纤维瘤病的精准治疗与个性化用药的发展，进一步强调了基因信息检测与分析1型神经纤维瘤病的重要性。

肿瘤靶向药物及精准治疗临床研究内容关键词：

认知缺陷, 1型神经纤维瘤病,社会认知,社交技能

肿瘤靶向治疗基因检测临床应用结果

1型神经纤维瘤病 (NF1) 是一种常见的单基因疾病，其特征在于多种皮肤、神经和肿瘤表现。众所周知，患有 NF1 的儿童与同伴互动较差，并且面临社交技能缺陷的风险。然而，很少有研究检查 NF1 成人的社会功能。基因解码基因检测旨在确定患有 NF1 的成年人是否有更大的社交技能受损风险，并确定社交技能缺陷的潜在风险因素。基因解码基因检测使用自我报告和观察者报告的社会行为测量评估了 62 名 NF1 成人和 39 名对照者的社交技能。基因解码基因检测证明，与对照组相比，患有 NF1 的成年人表现出的亲社会行为显着减少。这种缺陷与社会处理能力有关，在男性中更为明显。两组之间反社会行为的频率相当，但与 NF1 组的行为调节显着相关。这些研究基因解码基因检测的研究结果表明，NF1 个体的社交技能差是由于亲社会行为的缺陷，而不是反社会行为的增加。这将有助于设计旨在提高 NF1 患者社交技能的干预措施。关键词：认知缺陷； 1型神经纤维瘤病；社会认知;社交技能。

肿瘤发生与复发转移国际数据库描述：

Neurofibromatosis type 1 (NF1) is a common single-gene disorder characterised by a diverse range of cutaneous, neurological and neoplastic manifestations. It is well recognised that children with NF1 have poor peer interactions and are at risk for deficits in social skills. Few studies, however, have examined social functioning in adults with NF1. We aimed to determine whether adults with NF1 are at greater risk for impairment in social skills and to identify potential risk factors for social skills deficits. We evaluated social skills in 62 adults with NF1 and 39 controls using self-report and observer-report measures of social behaviour. We demonstrate that adults with NF1 exhibit significantly less prosocial behaviour than controls. This deficit was associated with social processing abilities and was more evident in males. The frequency of antisocial behaviour was comparable between the two groups, however was significantly associated with behavioural regulation in the NF1 group. These findings suggest that poor social skills in individuals with NF1 are due to deficits in prosocial behaviour, rather than an increase in antisocial behaviour. This will aid the design of interventions aimed at improving social skills in individuals with NF1.Keywords: Cognitive deficits; Neurofibromatosis type 1; Social cognition; Social skills.

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